Product Management | Software Development
June 2020 — Sept. 2020
Product management intern leading a 4-person team in developing an end-to-end hospitality management system that helps college students rent out their places while they’re away on breaks.
Visit website | Read more →
Data Science
August 2019 — Present
Data analyst and editor for the Yale Daily News. Telling stories with data and making key insights free and accessible for all.
Selected Articles:
Bioinformatics
August 2019 — Present
Student researcher. Determined to replace medical diagnoses with prognoses. Previously at Prof. Stephanie Halene's lab (Yale), now at Prof. Xihong Lin's lab (Harvard).
Published work:
-
Mutations in the gene coding for the U2AF1 protein are known to be responsible for many cases of acute myeloid leukemia (AML). However, very little is known about how these mutations lead to disease. Our analysis found that these mutated proteins may cause AML by abnormally modifying other genes involved in the essential processes of the cell cycle and DNA repair.
Read abstract →
-
In the past, mice have been "humanized" with human stem cell grafts in order to act as more accurate models for experimentation. However, all of these previous mouse models lack mature human blood cells, which are essential for studies of blood-related diseases, such as leukemia. Our team generated the first humanized mice with fully matured blood cells.
Read abstract →
-
DNA repair is known to be abnormal in individuals with acute myeloid leukemia (AML). When a protein essential for DNA repair called PARP was inhibited, we found that leukemia-initiating cells were reduced in mice engrafted with AML. This suggests that PARP inhibitors could be a potential treatment option for AML.
Read abstract →
